Reporter Speed Morgan (Rex Bell) helps Flash Barrett (Lloyd Whitlock) escape from the police and this gets him into Flash's gang where he poses as a gangster. Flash and his gang head west guning for Bill Miller (Bud Osborne) who failed to send some diamonds on to Flash. Speed hopes to bring Flash to justice but is in trouble when his true identity is revealed.

Broadway To Cheyenne starts off with a bunch of big city gangsters fighting and killing each other with Detective Breezy Kildare (Rex Bell) caught in the middle. When Breezy goes out west to the ranch where he grew up he runs into the same bunch of crooks. The gangsters are offering "protection" to the local ranchers. For the rest of the movie it's cowboys and gangsters.